Table 3.
Events/No. at Risk | Model 1, HR (95% CI)b | P Value | Model 2, HR (95% CI)c | P Value | Interaction P Valued | |
---|---|---|---|---|---|---|
Age, ye | 0.56 | |||||
<61 | 45/2979 | 1.19 (0.75‐1.89) | 0.47 | 1.30 (0.82‐2.06) | 0.27 | |
≥61 | 172/3415 | 1.32 (1.05‐1.67) | 0.017 | 1.37 (1.08‐1.73) | 0.0087 | |
Sex | 0.14 | |||||
M | 127/2958 | 1.50 (1.15‐1.96) | 0.0028 | 1.61 (1.23‐2.12) | 0.0006 | |
F | 90/3436 | 1.16 (0.84‐1.60) | 0.37 | 1.20 (0.86‐1.67) | 0.27 | |
Race/ethnicity | 0.69 | |||||
White | 87/2413 | 1.27 (0.92‐1.75) | 0.14 | 1.32 (0.95‐1.81) | 0.095 | |
Nonwhite | 130/3981 | 1.41 (1.08‐1.84) | 0.011 | 1.45 (1.10‐1.90) | 0.0079 |
Abbreviations: BMI, body mass index; CI, confidence interval; DM, diabetes mellitus; F, female; HDL‐C, high‐density lipoprotein cholesterol; HF, heart failure; HR, hazard ratio; ID, intrinsicoid deflection; LVH, left ventricular hypertrophy; M, male; ms, millisecond; SBP, systolic blood pressure.
HR presented for maximum time to ID per 10‐ms increase.
Adjusted for age, sex, race/ethnicity, education, and income.
Adjusted for Model 1 covariates plus heart rate, SBP, smoking, DM, BMI, cholesterol, HDL‐C, aspirin, statins, antihypertensive medications, and LVH.
Interactions tested using Model 2.
Stratified by the median age for study participants.