Figure 3. Chronic stress-induced decrease in the expression of the GABAAR δ subunit in the dentate gyrus.
a, Representative Western blots of GABAAR δ and γ2 subunit expression in minimally-handled controls and mice subjected to chronic restraint stress. b, The average optical density of GABAAR δ subunit expression is decreased in mice subjected to chronic stress compared to controls. n = 8 mice per experimental group; p < 0.01 using a Student’s unpaired t-test. c, The average optical density of GABAAR γ2 subunit expression is increased in mice subjected to chronic stress compared to controls. n = 11 – 19 mice per experimental group; p < 0.05 using an unpaired Student’s t-test.