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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Hippocampus. 2016 Jun 2;26(10):1276–1290. doi: 10.1002/hipo.22604

Figure 5. Reduced expression of the GABAAR δ subunit in the dentate gyrus of Gabrd/Pomc mice.

Figure 5

Representative images of immunoreactivity for the GABAAR δ subunit in Cre−/− littermates (a) and Gabrd/Pomc mice (b). c, Representative image of GFP reporter expression in Pomc-GFP mice, demonstrating the specificity of Cre expression in dentate gyrus granule cells. d, The average optical density of GABAAR δ subunit immunoreactivity is decreased in Gabrd/Pomc mice compared to Cre−/− littermates. n = 3 mice per experimental group. e, Representative Western blot of GABAAR δ subunit expression in Gabrd/Pomc mice and Cre−/− littermates. f, The average optical density of GABAAR δ subunit expression, quanitified using Western blot analysis, is decreased in Gabrd/Pomc mice Gabrd/Pomc mice compared to Cre−/− littermates. n = 6 mice per experimental group; * denotes significance of p<0.05 using a Student’s t-test.