Table 2.
Associations with 5-Year Mastectomy Cumulative Incidence
| Characteristic | Gray's Test P-value | Number of Outcomes | Person-Year | HR (95%CI) | P-value | |
|---|---|---|---|---|---|---|
| Breast radiation | <.0001 | |||||
| Yes | 97 | 9793.08 | 1 (Ref) | |||
| No* | 40 | 1509.5 | 2.33 | (1.56, 3.49) | <.0001 | |
| Age | 0.93 | |||||
| 70 - 74 | 53 | 4558.17 | 1.41 | (0.86, 2.34) | 0.18 | |
| 75 - 79 | 44 | 3527.75 | 1.41 | (0.89, 2.24) | 0.14 | |
| ≥ 80 | 40 | 3216.67 | 1 (Ref) | |||
| T Stage | 0.01 | |||||
| T1a + T1mic | 13 | 1004.67 | 1 (Ref) | |||
| T1b | 22 | 2639.58 | 0.63 | (0.31, 1.28) | 0.20 | |
| T1c* | 57 | 5257.17 | 0.75 | (0.40, 1.40) | 0.36 | |
| T2* | 45 | 2401.17 | 1.01 | (0.52, 1.96) | 0.97 | |
| Progesterone receptor status | 0.08 | |||||
| Positive | 5 | 942.5 | 1 (Ref) | |||
| Negative | 129 | 10230.5 | 2.01 | (0.82, 4.92) | 0.12 | |
| Indeterminate | 3 | 129.58 | 3.43 | (0.80, 14.73) | 0.10 | |
| Tumor Histology | 0.89 | |||||
| Ductal Carcinoma | 122 | 10172.42 | 1 (Ref) | |||
| Lobular Carcinoma | 5 | 415.33 | 1.47 | (0.60, 3.63) | 0.40 | |
| Other | 10 | 714.83 | 1.40 | (0.71, 2.74) | 0.34 | |
| Histologic grade | 0.11 | |||||
| Well differentiated | 4 | 796.83 | 1 (Ref) | |||
| Intermediate/moderate | 35 | 3386.83 | 2.21 | (0.78, 6.28) | 0.14 | |
| Poorly differentiated/Undifferentiated | 89 | 6352.25 | 2.62 | (0.95, 7.23) | 0.07 | |
| Not determined | 9 | 766.67 | 2.18 | (0.66, 7.16) | 0.20 | |
| Chemotherapy received | 0.34 | |||||
| Yes | 40 | 2885.92 | 1 (Ref) | |||
| No | 97 | 8416.67 | 0.90 | (0.60, 1.36) | 0.62 | |
| Comorbidity Index | 0.14 | |||||
| 0 | 41 | 4299.58 | 1 (Ref) | |||
| 1 | 26 | 1823.83 | 1.47 | (0.89, 2.41) | 0.13 | |
| ≥ 2 | 70 | 5179.17 | 1.32 | (0.88, 2.00) | 0.18 | |
| Race | 0.45 | |||||
| White | 120 | 9807.83 | 1 (Ref) | |||
| Black | 9 | 975.17 | 0.66 | (0.32, 1.36) | 0.26 | |
| Hispanic | 1 | 155.92 | 0.52 | (0.07, 3.68) | 0.52 | |
| Other/ Unknown | 7 | 363.67 | 1.52 | (0.67, 3.44) | 0.31 | |
| Marital Status | 0.23 | |||||
| Married | 64 | 4902.42 | 1 (Ref) | |||
| Unmarried | 72 | 6046.33 | 0.81 | (0.57, 1.16) | 0.23 | |
| Unknown | 1 | 353.83 | 0.17 | (0.02, 1.22) | 0.08 | |
| Year of Diagnosis | 0.12 | |||||
| 1993-1999 | 27 | 3124.92 | 1 (Ref) | |||
| 2000-2004* | 68 | 4935.75 | 1.58 | (1.00, 2.50) | 0.05 | |
| 2005-2009 | 42 | 3241.92 | 1.32 | (0.80, 2.18) | 0.27 | |
| SEER Region | 0.07 | |||||
| West | 59 | 4824.67 | 1 (Ref) | |||
| Midwest | 25 | 1724.42 | 1.40 | (0.85, 2.31) | 0.18 | |
| Northeast | 22 | 2777.58 | 0.69 | (0.42, 1.13) | 0.14 | |
| South | 31 | 1975.92 | 1.24 | (0.78, 1.99) | 0.36 | |
| Urban Residence | 0.03 | |||||
| Metro | 114 | 10054.08 | 1 (Ref) | |||
| Urban/ Rural | 23 | 1248.5 | 1.24 | (0.77, 2.02) | 0.38 | |
| Census Track Level Poverty | 0.01 | |||||
| 0.00%-9.99% | 80 | 7612.67 | 1 (Ref) | |||
| 10.00%-19.99% | 45 | 2472.08 | 1.51 | (1.00, 2.30) | 0.05 | |
| 20.00%+ | 12 | 1217.83 | 0.81 | (0.43, 1.55) | 0.53 | |