Table 4.
Associations with 5-Year Breast Cancer Specific Death Cumulative Incidence
| Characteristic | Gray's Test P-value | Number of Outcomes | Person-Year | HR (95%CI) | P-value | |
|---|---|---|---|---|---|---|
| Breast radiation | <.0001 | |||||
| Yes | 188 | 10417.17 | 1 (Ref) | |||
| No* | 97 | 1636.33 | 2.15 | (1.63, 2.82) | <.0001 | |
| Age | <.0001 | |||||
| 70 - 74* | 80 | 4910 | 0.73 | (0.53, 1.01) | 0.06 | |
| 75 - 79 | 80 | 3744.67 | 0.86 | (0.63, 1.16) | 0.32 | |
| ≥ 80 | 125 | 3398.83 | 1 (Ref) | |||
| T Stage | <.0001 | |||||
| T1a + T1mic | 10 | 1078.83 | 1 (Ref) | |||
| T1b | 28 | 2796.25 | 1.01 | (0.49, 2.08) | 0.99 | |
| T1c* | 113 | 5574.67 | 1.85 | (0.98, 3.55) | 0.07 | |
| T2* | 134 | 2603.75 | 3.77 | (2.12, 7.26) | <.0001 | |
| Progesterone receptor status | 0.07 | |||||
| Positive | 13 | 986.83 | 1 (Ref) | |||
| Negative | 270 | 10928.5 | 1.35 | (0.77, 2.35) | 0.30 | |
| Indeterminate | 2 | 138.17 | 1.01 | (0.23, 4.31) | 0.99 | |
| Tumor Histology | 0.07 | |||||
| Ductal Carcinoma | 267 | 10834 | 1 (Ref) | |||
| Lobular Carcinoma | 9 | 437.25 | 1.11 | (0.59, 2.11) | 0.75 | |
| Other | 9 | 782.25 | 0.51 | (0.27, 1.05) | 0.07 | |
| Histologic grade | <.0001 | |||||
| Well differentiated | 3 | 843 | 1 (Ref) | |||
| Intermediate/moderate | 63 | 3580.92 | 3.95 | (1.24, 12.56) | 0.02 | |
| Poorly differentiated/Undifferentiated | 207 | 6804.25 | 5.81 | (1.84, 18.35) | 0.00 | |
| Not determined | 12 | 825.33 | 3.64 | (1.03, 12.90) | 0.05 | |
| Chemotherapy received | 0.58 | |||||
| Yes | 69 | 3083.17 | 1 (Ref) | |||
| No | 216 | 8970.33 | 1.11 | (0.81, 1.52) | 0.52 | |
| Comorbidity Index | 0.02 | |||||
| 0 | 86 | 4592.17 | 1 (Ref) | |||
| 1 | 47 | 1945.67 | 1.11 | (0.77, 1.59) | 0.59 | |
| ≥ 2 | 152 | 5515.67 | 1.10 | (0.83, 1.45) | 0.51 | |
| Race in General | 0.96 | |||||
| White | 248 | 10426.75 | 1 (Ref) | |||
| Black | 24 | 1070.08 | 0.91 | (0.56, 1.51) | 0.73 | |
| Hispanic | 3 | 164.08 | 0.68 | (0.22, 2.15) | 0.52 | |
| Other/ Unknown | 10 | 392.58 | 1.23 | (0.62, 2.45) | 0.55 | |
| Marital Status | 0.13 | |||||
| Married | 107 | 5243.92 | 1 (Ref) | |||
| Unmarried | 167 | 6441.17 | 0.95 | (0.74, 1.23) | 0.69 | |
| Unknown | 11 | 368.42 | 1.07 | (0.56, 2.03) | 0.85 | |
| Year of Diagnosis | 0.87 | |||||
| 1993-1999 | 74 | 3367.83 | 1 (Ref) | |||
| 2000-2004 | 124 | 5223.83 | 0.94 | (0.70, 1.27) | 0.68 | |
| 2005-2009 | 87 | 3461.83 | 0.83 | (0.59, 1.15) | 0.26 | |
| SEER Region | 0.09 | |||||
| West | 113 | 5127.67 | 1 (Ref) | |||
| Midwest | 35 | 1850.08 | 0.93 | (0.62, 1.40) | 0.73 | |
| Northeast* | 87 | 2943.58 | 1.37 | (1.01, 1.85) | 0.04 | |
| South | 50 | 2132.17 | 1.07 | (0.76, 1.52) | 0.70 | |
| Urban Residence | 0.33 | |||||
| Metro | 249 | 10750.75 | 1 (Ref) | |||
| Urban/ Rural | 36 | 1302.75 | 1.21 | (0.84, 1.74) | 0.32 | |
| Census Track Level Poverty | 0.81 | |||||
| 0.00%-9.99% | 187 | 8083.58 | 1 (Ref) | |||
| 10.00%-19.99% | 68 | 2673.08 | 1.05 | (0.77, 1.42) | 0.77 | |
| 20.00%+ | 30 | 1296.83 | 0.98 | (0.62, 1.55) | 0.92 | |