Table 5.

Proteins with Potential PPI Binding Sites Identified from Search Against PrePPI

Symbol	Name	Binding site	Predicted PPI
			Model	Symbol	Name
AK3	GTP:AMP phosphotransferase AK3, mitochondrial	1ZD8A2	2BWJ	AK5	Adenylate kinase isoenzyme 5
ANK1	Ankyrin-1	1N11A3	2JAB	ILK	Integrin-linked protein kinase
CHN1	N-chimaerin	3CXLA3	1OW3	RAC1	Ras-related C3 botulinum toxin substrate 1
HOGA1	4-hydroxy-2-oxoglutarate aldolase, mitochondrial	3S5OA1†	3DAQ	HOGA1	4-hydroxy-2-oxoglutarate aldolase, mitochondrial
HPD	4-hydroxyphenylpyruvate dioxygenase	3ISQA1†	1SQI	HPDL	4-hydroxyphenylpyruvate dioxygenase-like protein
HPD	4-hydroxyphenylpyruvate dioxygenase	3ISQA5	1SQI	HPDL	4-hydroxyphenylpyruvate dioxygenase-like protein
LCN	Lipocalin-1	3EYCA1†	2F91	OVCH1	Ovochymase-1
NCS1	Neuronal calcium sensor 1	1G8IB1	1AUI	PPP3CA	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
NCS1	Neuronal calcium sensor 1	1G8IB2†	1AUI	PPP3CA	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
RAP1GAP	Rap1 GTPase-activating protein 1	1SRQA1	3BRW	RAP1A	Ras-related protein Rap-1A
RHCG	Ammonium transporter Rh type C	3HD6A1	2NUU	RHAG	Ammonium transporter Rh type A
RHCG	Ammonium transporter Rh type C	3HD6A4	2NUU	RHAG	Ammonium transporter Rh type A
RHCG	Ammonium transporter Rh type C	3HD6A5	2NUU	RHAG	Ammonium transporter Rh type A
SHMT2	Serine hydroxymethyltransferase, mitochondrial	3OU5A1	3GBX	SHMT2	Serine hydroxymethyltransferase, mitochondrial
STXBP2	Syntaxin-binding protein 2	4CCAA2	3C98	STX1A	Syntaxin-1A
THEM5	Acyl-coenzyme A thioesterase THEM5	4AE7A1	1Q4T	THEM4	Acyl-coenzyme A thioesterase THEM4
ZBTB32	Zinc finger and BTB domain-containing protein 32	3M5BB1	3BIM	BCL6	B-cell lymphoma 6 protein

^†The binding site is druggable (DS ≥ 1.0)