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. 2016 Sep 21;8:212. doi: 10.3389/fnagi.2016.00212

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Copyright © 2016 Kalogeraki, Pielecka-Fortuna, Hüppe and Löwel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Short-term running after an S1-stroke restored OD-plasticity in adult (>P119) mouse V1. Optically recorded maps of the contralateral (contra) and ipsilateral (ipsi) eye of non-lesioned (14dRW-sham: A,C) and PT-lesioned 14dRW mice raised in a SC but transferred to a RW-cage after stroke (14dRW-PT; B,D), Data presented as in Figure 2. Activity and polar maps of the binocular part of the left V1 and ODI values of the left hemisphere, 2-dimensional OD-maps and ODI-histograms without (A,B) or with MD (C,D). Note that animals with MD showed a significant OD-shift in both groups of 14dRW-mice (blue arrow indicates reduced ODIs), i.e., OD-plasticity was restored in adult mice by 14dRW-experience regardless of the treatment (sham or PT). Scale bar: 1 mm.