Table 2.
SBM components with strongest CAP-group effects (p ≤ 0.0001).
| Component | CAP effect statistic (F3,688) | Most significant regions | Left/right volume (cc) | Left/right maximum Z coordinates (x, y, z) |
|---|---|---|---|---|
| A | 12.1915 | Superior temporal pole | 2.4/2.3 | 7.4 (−38, 13, −24)/7.2 (44, 16, −25) |
| Superior temporal | 2.8/2.2 | 5.8 (−49, −3, −3)/5.9 (51, 1, −8) | ||
| Anterior cingulate/medial | 1.7/2.2 | 5.1 (1, 44, 11)/5.7 (3, 50, −4) | ||
| Frontal parahippocampal | 0.3/0.2 | 3.9 (−14, −4, −23)/4.0 (18, 1, −24) | ||
| B | 37.733 | Caudate | 3.8/3.9 | 12.5 (0.10, 17, 5)/11.6 (14, 20, 4) |
| Thalamus | 1.8/2.1 | 8.7 (−5, −13, 16)/8.3 (10, −15, 16) | ||
| C | 11.948 | Precentral/mid frontal | 6.9/5.3 | 5.2 (−37, −6, 62)/4.9 (43, −4, 60) |
| Precentral/superior frontal | 4.2/2.7 | 4.6 (−34, −1, 55)/4.6 (30, −2, 63) | ||
| Supplementary motor | 1.1/1.0 | 4.2 (−5, −7, 66)/4.1 (13, −0, 66) | ||
| E | 11.873 | Supplementary motor | 2.9/5.4 | 7.7 (2, 15, 49)/6.2 (6, 15, 47) |
| Frontal superior | 0.3/0.1 | 5.5 (0, 31, 33)/2.8 (2, −72, 31) | ||
| Medial/cuneus | 4.6/3.4 | 7.1 (2, −33, 60)/6.4 (6, −31, 58) | ||
| Paracentral lobule | 3.6/3.2 | 7.0 (2, −33, 60)/5.8 (6, 11, 46) | ||
| Mid cingulate/precuneus | 4.0/5.1 | 5.6 (2, −42, 56)/5.5 (6, −44, 62) | ||
| M | 9.220 | Calcarine | 0.6/7.2 | 4.7 (−25, −60, 7)/10.6 (27, −50, 13) |
| Left precuneus | 1.9 | 6.9 (−25, −51, 14) | ||
| Left mid temporal | 1.0 | 4.5 (−46, −51, 12) | ||
| Left superior occipital | 0.5 | 4.1 (−20, −68, 20) |
Regions within components A, B, C, E, and M, including CAP-group effect F statistic derived from the Sidak post hoc, bilateral maximum Z scores with corresponding Montreal Neurological Institute (MNI) coordinates, and volumes in cubic centimeters (cc).