Fig. 1.

Impact of dengue vaccination without immune-interactions. Results show the outcome of a routine vaccination campaign based on 50 individual model runs, using a vaccination coverage of 75% at the age of 6 years (vaccination start at t = 0, vertical dashed lines). Solid lines in timeseries plots are the 1-year averages, with between-run variability shown as shaded areas. Incidence is presented per 100K individuals. (A) Timeseries showing changes in total, primary and secondary infections (grey, red and blue respectively). (B) Boxplots (see Section 4) showing the distribution in vaccine impact as the percent reduction in total, primary and secondary incidence (grey, red and blue, respectively) for 3 relevant periods post-vaccination. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of the article.)