HHcy reduced inflammatory markers and increased the MMP system markers in both the IgG2a and 3D6 groups. Data are shown as a fold change from APP/PS1, control, and IgG2a. Relative gene expression for proinflammatory markers (A), would healing/repair markers (B), immune complex-mediated markers (C), and MMP2 and MMP9 system markers (D). *p < 0.05, compared with APP/PS1, control, and IgG2a. **p < 0.01, compared with APP/PS1, control, and IgG2a.