FIG 5 .

BCG protects M. tuberculosis-infected NZO mice from diabetes. (A) Blood glucose measurements obtained from naive and BCG-vaccinated NZO mice at 4 and 14 weeks postinfection. Mice were fasted for 6 h prior to obtaining blood glucose measurements. Mice were considered diabetic if they had a blood glucose concentration greater than 200 mg/dl. (B) Percent weight changes of naive and BCG-vaccinated mice relative to initial mouse weights at 4 and 14 weeks postinfection. Correlation of blood glucose versus lung CFU (C) and correlation of blood glucose versus weight change (D) at 14 weeks postinfection in naive and BCG-vaccinated mice. Each data point is the value for an individual NZO mouse at each specified time point. Naive and BCG-vaccinated groups were compared by Student’s t test. *, P < 0.05; **, P < 0.01; ***, P < 0.001.