Table 3. Correlation coefficients of log FGF21 and log NT-pro-BNP for the association with clinical and echocardiographic variables.

Variable	Log FGF21		Log NT-pro-BNP
	R	P value	R	P value
Log FGF21	—	—	0.493	<0.001
Log NT-pro-BNP	0.493	<0.001	—	—
Age (years)	0.119	0.067	0.260	<0.001
Gender (male = 1)	−0.140	0.030	−0.035	0.595
Body mass index (kg/m2)	0.052	0.428	−0.192	0.003
Hypertension	0.285	<0.001	0.239	<0.001
Diabetes	0.220	0.001	0.282	<0.001
NYHA class III-IV HF	0.178	0.006	0.253	<0.001
Coronary artery disease	0.139	0.032	0.292	<0.001
Peripheral artery disease	0.152	0.019	0.243	<0.001
Laboratory data
Hemoglobin (mg/dL)	−0.324	<0.001	−0.424	<0.001
eGFR (mL/min/1.73m2)	−0.472	<0.001	−0.527	<0.001
Total cholesterol (mg/dL)	0.018	0.787	−0.002	0.970
Triglyceride (mg/dL)	0.281	<0.001	0.006	0.924
FBS (mg/dL)	0.191	0.004	0.226	0.001
CRP (mg/dL)	0.181	0.076	0.230	0.023
Hemodynamic studies
Central DBP (mmHg)	−0.169	0.045	−0.185	0.028
Pulse pressure (mmHg)	0.086	0.301	0.197	0.019
LVEDP (mmHg)	0.253	<0.001	0.205	0.004
Echocardiography
LA dimension (mm)	0.259	<0.001	0.344	<0.001
IVST (mm)	0.254	<0.001	0.282	<0.001
LV mass index (g/m2)	0.268	<0.001	0.425	<0.001
e′ velocity (cm/s)	−0.283	<0.001	−0.292	<0.001
E/e′ ratio	0.321	<0.001	0.401	<0.001
Deceleration time (msec)	−0.060	0.372	−0.113	0.088
RVSP (mmHg)	0.140	0.043	0.326	<0.001

NYHA Fc = the New York Heart Association functional classification, eGFR = estimated glomerular filtration rate, FBS = fasting blood sugar, CRP = C-reactive protein, DBP = diastolic blood pressure, LVEDP = left ventricular end-diastolic pressure, LA = left atrial, IVST = interventricular septal thickness, LV = left ventricular, RVSP = right ventricular systolic pressure.