Table 3. Clinical and Laboratory Characteristics of Control and Syphilis Patients.
Control 1 (blood) (n = 63) | Control 2 (CSF) (n = 29) | Non-neurosyphilis (n = 123) | Neurosyphilis |
||
---|---|---|---|---|---|
Asymptomatic (n = 82) | Symptomatic (n = 109) | ||||
Male (%) | 48 (68.5) | 18 (62.1) | 71 (57.7) | 52 (63.4) | 98 (89.9) |
Age (Median, IQR) | 44 (25–55) | 46 (27–61) | 52.5 (42.25–59.5) | 52 (39–59) | 53.5 (47–59) |
1/Serum RPR titer (median, IQR) | 0 (0–0) | 0 (0–0) | 32 (8–64) | 64 (32–128) | 63 (32–64) |
CSF-WBC, cells/μl (median, IQR) | ND | 1 (0–5) | 1.1 (0–4.3) | 8.8 (2.2–39.05) | 9.9 (2–35.8) |
CSF protein, g/l (Median, IQR) | ND | 0.23 (0.1–0.4) | 0.29 (0.23–0.34) | 0.43 (0.29–0.57) | 0.63 (0.46–0.89) |
CSF VDRL (+) (%) | ND | 0 (0) | 0 (0) | 67 (81.7) | 109 (100) |
CSF VDRL (−) and CSF-TPPA (+) (%) | ND | 0 (0) | 35 (28.2) | 15 (18.3) | 0 (0) |
Data are given as median (IQR), or frequencies.
Abbreviations: RPR, Rapid Plasma Regain test; CSF, cerebrospinal fluid; VDRL, Venereal Research Laboratory; TPPA, Treponema pallidum particle agglutination assay; WBC, white blood cells; ND, not done.