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. 2016 Sep 21;6:33569. doi: 10.1038/srep33569

Table 3. Clinical and Laboratory Characteristics of Control and Syphilis Patients.

  Control 1 (blood) (n = 63) Control 2 (CSF) (n = 29) Non-neurosyphilis (n = 123) Neurosyphilis
Asymptomatic (n = 82) Symptomatic (n = 109)
Male (%) 48 (68.5) 18 (62.1) 71 (57.7) 52 (63.4) 98 (89.9)
Age (Median, IQR) 44 (25–55) 46 (27–61) 52.5 (42.25–59.5) 52 (39–59) 53.5 (47–59)
1/Serum RPR titer (median, IQR) 0 (0–0) 0 (0–0) 32 (8–64) 64 (32–128) 63 (32–64)
CSF-WBC, cells/μl (median, IQR) ND 1 (0–5) 1.1 (0–4.3) 8.8 (2.2–39.05) 9.9 (2–35.8)
CSF protein, g/l (Median, IQR) ND 0.23 (0.1–0.4) 0.29 (0.23–0.34) 0.43 (0.29–0.57) 0.63 (0.46–0.89)
CSF VDRL (+) (%) ND 0 (0) 0 (0) 67 (81.7) 109 (100)
CSF VDRL (−) and CSF-TPPA (+) (%) ND 0 (0) 35 (28.2) 15 (18.3) 0 (0)

Data are given as median (IQR), or frequencies.

Abbreviations: RPR, Rapid Plasma Regain test; CSF, cerebrospinal fluid; VDRL, Venereal Research Laboratory; TPPA, Treponema pallidum particle agglutination assay; WBC, white blood cells; ND, not done.