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. Author manuscript; available in PMC: 2016 Sep 21.
Published in final edited form as: J Immunol. 2015 Aug 7;195(6):2540–2551. doi: 10.4049/jimmunol.1501019

Figure 4. Listeria-derived PG’s are 10 to 100-fold more antigenic than Corynebacterium or mammalian PG.

Figure 4

A. Listeria PG from fractions C, D, and E were compared in activity to Corynebacterium (Cg) PG when co-cultured in triplicate with either 14S.6 or TBA7 hybridomas in the presence of RAW-CD1d or RAW (not shown) cells. B. The fold-difference in concentration required for similar activity to Corynebacterium PG was calculated. C. Synthetic Listeria and mammalian PGs were assayed for activity as in A. The fold-difference in concentration required for similar activity to synthetic mammalian PG was assayed. Panel A is representative of three independent experiments, panel B is a combination of three experiments, and panel C is representative (left panel) or a combination (right panel) of two independent experiments. *p<0.05, **p<0.01, ***p<0.05 by one-way ANOVA. All graphs are presented as mean ± SEM.