Table 3.

Association between Ki67 expression and clinicopathological variables (N = 146)

Variable	Ki67 expression
	≤ 10%	> 10%	Tot	P-value
Nuclear grading
1	22	1	23
2	72	23	95	0.001*
3	14	14	28
Gleason Score
< 7	56	8	64	0.001*
≥ 7	51	30	81
missing 1
Age at diagnosis (median, years)
≤ 71	53	19	72	0.922
> 71	55	19	74
Age at diagnosis (continuous)	108	38	146	0.973
NSE expression
Negative	21	4	25	0.073
Positivea	28	16	44
missing 77
CgA expression
Negative	37	10	47	0.217
Positivea	24	12	36
missing 40
Syp expression
Negative	31	8	39	0.326
Positivea	33	14	47
missing 60
Type of intervention
TURP	78	33	111	0.081
Prostatectomy	29	5	34
missing 1
Total	108	38	146

^*Significant value

^aOnly diffuse expression was considered as positive staining;