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. Author manuscript; available in PMC: 2016 Sep 21.
Published in final edited form as: Biomaterials. 2014 Jan 15;35(10):3252–3262. doi: 10.1016/j.biomaterials.2013.12.093

Table 1.

Potency and efficacy of mESCs adhesion to ECM proteins.

ECM protein Potency (EC50) Efficacy R2
Fibronectin 11.6 ± 0.4 97.8 ± 1.0% 0.9778
Vitronectin 1275.3 ± 29.0 84.9 ± 1.4% 0.9943
Thrombospondin-1 607.0 ± 5.3 42.6 ± 1.1% 0.9878
LM 511 72.2 ± 2.4 111.0 ± 1.4% 0.9960
LM 521 77.9 ± 6.2 97.7 ± 1.5% 0.9870
LM 332 177.7 ± 16.4 100 ± 3.2% 0.9802
LM 421 202.6 ± 13.6 86.1 ± 2.0% 0.9883
LM 211 409.7 ± 29.4 93.2 ± 2.9% 0.9840
LM 111 504.4 ± 55.2 67.7 ± 2.0% 0.9769
LM 411 947.9 ± 92.0 101.7 ± 5.5% 0.9852

Potency is expressed as EC50 (ng/well) of the immobilized proteins and efficacy is expressed as the percentage cells adhered in comparison to adhesion to the positive control (1 μg/well of immobilized fibronectin). The data are mean ± SEM of three independent experiments performed in triplicates (n = 9). R2 is the correlation coefficient of the four parameters logistic curve fitted to calculate the potency and efficacy. LM –laminin.