Table 3.

Seizure Outcomes by Caffeine Dose

	Standard-dose caffeine N = 30	High-dose caffeine N = 29	p
Seizure incidence, n (%)	12 (40)	17 (58)	0.19
Seizure burden, mean (SEM), seconds	48.9 (17.4)	170.9 (75.4)	0.10
Log seizure burden, mean (SEM)	1.70 (0.40)	2.78 (0.48)	0.10
Clinical seizure requiring treatment, n (%)	3 (10)	2 (7)	1.0
Status epilepticus,an (%)	0 (0)	1 (3)	0.49

^aDefined as a seizure greater than 5 minutes in length or more than one seizure in a 5-minute period.

SEM, standard error of the mean.