Table 1.

Results of univariate analyses of features associated with final diagnosis (all cases included).

	CPAM (n = 103)	PPB (n = 112)	OR for CPAM vs PPB	PPV for CPAM	Sensitivity	Specificity	p
Male	54/103	66/112	0.8 (0.4–1.3)	45%	0.52	0.41	0.4
Age at presentation in lesions not detected prenatally (months)	Median 48 (IQR 1–72)	Median 11.5 (IQR 4–24)	–	–	–	–	0.1b
Prenatal detection	86/103	6/112	89.4 (33.8–236.6)	93%	0.83	0.95	<0.0001
Absence of symptoms	70/103	23/110	8.0 (4.3–14.9)	75%	0.70	0.79	<0.0001
Hyperinflated regiona	39/98	9/111	6.6 (3.0–14.5)	81%	0.40	0.92	<0.0001
Absence of pneumothoraxa	8/97	27/111	3.6 (1.5–8.3)	51%	0.92	0.24	0.003
Unilateral (vs bilateral) abnormalitya	94/98	94/111	4.3 (1.4–13.1)	50%	0.96	0.15	0.01
Unilobar (vs multilobar) abnormality on one sidea	90/98	93/111	2.2 (0.9–5.3)	49%	0.92	0.16	0.1
Solid component on CT	30/96	5/90	7.7 (2.8–21.0)	86%	0.31	0.94	<0.0001
Systemic feeding vessel on CT	24/97	0/92	61.7 (3.7–1031.8)	100%	0.25	1.0	<0.0001
No mediastinal shifta	69/97	77/111	1.1 (0.6–2.0)	47%	0.71	0.31	0.9
Multilocular cyst on CT	67/88	73/89	0.7 (0.3–1.5)	48%	0.76	0.18	0.4
Simple (vs complex) cyst on CT	68/82	22/89	14.8 (7.0–31.3)	75%	0.83	0.75	<0.0001
Size of largest cyst (mm)	Median 18 (IQR 12.5–40); n = 63	Median 50 (IQR 33–70); n = 57	–	–	–	–	<0.0001b
DICER1 gene mutation negative	1/1	8/24	5.8 (0.2–158.9)	11%	1.0	0.66	0.36

Denominators for each data point are shown to account for missing data; IQR — interquartile range; PPV— positive predictive value.

^aOn X-ray or CT.

^bMann–Whitney test.