Fig. 3.

Gene expression and biological processes are associated with GLDS. a A QQ-plot where the P values for an association between gene expression and the first principle component of the completed drug sensitivity matrix are plotted against a theoretical uniform distribution. A deviation from the diagonal line in all three datasets is indicative of an enrichment of low P values. b GSEA enrichment plots for enrichment of Gene Ontology biological processes against GLDS in CGP. Data are shown for two of the most significant processes: “Growth” (left) and “Programmed Cell Death” (right)