Table 2.
Distribution of EGFR, KRAS and ALK mutations according to gender and smoking statusa
| Gender | Smoking status | ||||
|---|---|---|---|---|---|
| M | F | S | F | N | |
| EGFR mutations present | 11 | 40 | 8 | 11 | 32 |
| Exon 19 deletion | 2 | 21 | 5 | 4 | 14 |
| L858R | 6 | 14 | 2 | 4 | 14 |
| G719X | 1 | 3 | 1 | 1 | 2 |
| Exon 20 insertions | 1 | 1 | 0 | 1 | 1 |
| G719X + S768I | 1 | 0 | 0 | 1 | 0 |
| L858R + T790M | 0 | 1 | 0 | 0 | 1 |
| KRAS mutations present | 84 | 29 | 63 | 42 | 8 |
| Codon 12/13 | 79 | 28 | 59 | 41 | 7 |
| Codon 61 | 5 | 1 | 4 | 1 | 1 |
| ALK translocation | 2 | 10 | 3 | 1 | 8 |
Legend: aData presented as absolute numbers. M male, F female, S smoker, F former smoker, N never-smoker, numbers in bold indicate a statistically significant difference