Table 4. Sensitivity and specificity of the individual and the fusion antigens in detecting tuberculosis.
Antigen variants | Sensitivity % | Specificity % | ||
---|---|---|---|---|
Total TB samples n = 180 | Smear positive n = 94 | Smear negative n = 86 | ||
HSPX | 56 (31.1%) | 33 (35.1%) | 23 (26.7%) | 98 |
PE35 | 82 (45.5%) | 48 (51.0%) | 34 (39.5%) | 100 |
tnPstS1a | 76 (42.2%) | 45 (47.8%) | 31 (36.0%) | 100 |
FbpC1b | 108 (60%) | 67 (71.2%) | 41 (47.6%) | 100 |
HSPX-tnPstS1 | 104 (57.7%) | 61 (64.8%) | 43 (50.0%) | 99 |
HSPX-PE35 | 98 (54.4%) | 56 (59.5%) | 44 (51.1%) | 98 |
HSPX-FbpC1 | 100 (55.5%) | 52 (55.3%) | 48 (55.8%) | 100 |
HSPX+tnPstS1* | 100 (55.5%) | 58 (61.7%) | 41 (47.6%) | 99 |
HSPX+PE35* | 94 (52.2%) | 55 (58.5%) | 41 (47.6%) | 98 |
HSPX+FbpC1* | 130 (72.22%) | 79 (84.04%) | 51 (59.30%) | 98 |