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. 2016 Sep 21;11(9):e0163349. doi: 10.1371/journal.pone.0163349

Table 4. Sensitivity and specificity of the individual and the fusion antigens in detecting tuberculosis.

Antigen variants Sensitivity % Specificity %
Total TB samples n = 180 Smear positive n = 94 Smear negative n = 86
HSPX 56 (31.1%) 33 (35.1%) 23 (26.7%) 98
PE35 82 (45.5%) 48 (51.0%) 34 (39.5%) 100
tnPstS1a 76 (42.2%) 45 (47.8%) 31 (36.0%) 100
FbpC1b 108 (60%) 67 (71.2%) 41 (47.6%) 100
HSPX-tnPstS1 104 (57.7%) 61 (64.8%) 43 (50.0%) 99
HSPX-PE35 98 (54.4%) 56 (59.5%) 44 (51.1%) 98
HSPX-FbpC1 100 (55.5%) 52 (55.3%) 48 (55.8%) 100
HSPX+tnPstS1* 100 (55.5%) 58 (61.7%) 41 (47.6%) 99
HSPX+PE35* 94 (52.2%) 55 (58.5%) 41 (47.6%) 98
HSPX+FbpC1* 130 (72.22%) 79 (84.04%) 51 (59.30%) 98

*Combined sensitivities were corrected by reducing the number of the samples which showed presence of both antibodies. As reported previously

a[28],

b[29].