Table 2.

Functional imaging results of the changes in the main learning effect following aerobic exercise training in PD.

Area	X mm	Y mm	Z mm	K	Z	psvc
2.1. Main effect of session on sequence learning [POST – PRE] × [Sequence – Random]
PD
Right temporal lobe	30	12	− 36	92	3,85	0,002
Left temporal lobe	− 30	12	− 38	36	3,45	0,008
Left striatum ventral	− 18	6	− 12	48	3,76	0,003
Left hippocampus	− 34	− 16	− 12	99	3,66	0,004
Right cerebellum lobules 8 and 9	16	− 46	− 54	38	3,1	0,022
Left cerebellum lobules 8 and 9	− 20	− 42	− 52	38	3,14	0,02
Right cerebellum crus 1	28	− 72	− 38	51	3,1	0,022
2.2. Main effect of session on sequence learning [POST – PRE] × [Sequence – Random] regressed against changes in VO2max
Positive
Left hippocampus	− 18	− 34	− 2	182	3,19	0,017
Left hippocampus	− 18	− 24	− 10	23	3,12	0,021
Right hippocampus	36	− 32	− 8	170	3,4	0,01
Left putamen dorsal	− 28	0	18	45	3,04	0,025
Negative
Cerebellum lobule 7	− 2	− 76	− 24	167	3,98	0,001
Left cerebellum lobules 8 and 9	− 4	− 62	− 36	65	3,17	0,018
	− 16	− 60	− 46	110	3,11	0,021
Right cerebellum lobules 8 and 9	26	− 64	− 46	58	3,23	0,015

Statistical inferences were performed at a threshold of p < 0.05 after correction for multiple comparisons over small spherical volumes (SVC). K represents the number of voxels in each cluster reported (determined at a threshold of p = 0.005).