Table 3.

Functional imaging results of the main sequence learning effect following aerobic exercise training between PD and HC.

Area	X mm	Y mm	Z mm	K	Z	psvc
3.1. Main effect of session on sequence learning [POST – PRE] × [Sequence – Random]
PD-HC
Left cerebellum lobules 8 and 9	− 2	− 62	− 40	95	3,5	0,007
	− 20	− 48	− 54	181	3,41	0,009
	− 24	− 48	− 44	169	3,3	0,013
Right globus pallidus	14	2	− 10	11	3,15	0,019
Left striatum ventral	− 18	6	− 12	15	3,1	0,022
Left hippocampus	− 36	− 16	− 14	5	2,68	0,06a
HC-PD
No significant responses
3.2. Main effect of session on sequence learning [POST – PRE] × [Sequence – Random] regressed against changes in VO2max
PD-HC
Positive
Right hippocampus	20	− 28	− 6	38	3,15	0,019
Negative
Cerebellum lobule 7	− 2	− 76	− 24	95	3,48	0,007
Left cerebellum lobules 8 and 9	0	− 64	− 32		2,85	0,041
HC-PD
Positive
No significant responses
Negative
No significant responses

Statistical inferences were performed at a threshold of p < 0.05 after correction for multiple comparisons over small spherical volumes (SVC). K represents the number of voxels in each cluster reported (determined at a threshold of p = 0.005).

^aMarginally significant.