Skip to main content
. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Breast Cancer Res Treat. 2016 Sep 1;159(3):535–543. doi: 10.1007/s10549-016-3965-y

Table 3.

Analysis of Covariance Models By HRQOL Domain

25-Month HRQOL
Physical Social Emotional Functional BC-Specific Spiritual
5-Month HRQOL 0.46*** 0.68*** 0.54**** 0.52*** 0.58*** 0.68***
Demographics
Black race (ref=white) −0.17 −0.18 0.54** −0.52* 0.04 1.12**
Age at diagnosis 0.04** 0.03* 0.04*** 0.03* 0.06*** 0.04**
Smoking status (ref=never)
    Former 0.08 −0.27 −0.02 −0.21 −0.31 0.31
    Current −1.34** −0.77* −1.32*** −1.84*** −2.03*** −2.25***
Socioeconomics
Marital status (ref=not married) −0.08 −0.31 0.12 0.24 0.02 0.51
Education level (ref=<HS)
    HS & Post HS 0.76 0.85* 0.56 1.75*** 0.39 0.36
    College+ 1.53** 0.77 0.63 1.95*** 0.57 0.16
Insurance status (ref=private)
    Public −1.55*** 0.01 −0.43* −1.65*** −1.35*** −0.69
    Uninsured −1.72** −0.25 −0.01 −2.02*** −2.14*** −0.25
Comorbid Conditions
Diabetes (ref=no) −0.34 −0.48 −0.23 −0.33 0.52 0.34
COPD (ref=no) −0.93 −0.59 −0.34 −1.45* −0.91 −0.01
Heart Disease (ref=no) −1.04* −0.29 −0.88* −1.22* −0.51 −1.44*
Obesity (ref=no) −0.90*** −0.05 −0.33* −0.66** −1.03*** −0.33
Hypertension (ref=no) −0.11 −0.24 −0.25 −0.21 −0.25 −0.34
Treatments
Surgery (ref=lumpectomy)
    Mastectomy −0.29 −0.11 −0.07 −0.01 −0.56 −0.15
    Not specified 0.36 0.15 1.41 0.65 −0.57 1.89
Chemotherapy (ref=none) 0.24 −0.13 0.03 0.65* 0.52 −0.08
Radiation (ref=none) 0.03 −0.03 −0.02 0.18 0.04 −0.12
Herceptin (ref=none) −0.43 −0.11 −0.35 −0.51 −0.51 −0.35
Tumor characteristics
Stage (ref=Stage I)
    II −0.36 −0.23 −0.28 −0.31 −0.94** −0.13
    III −0.15 0.04 −0.18 −0.15 −1.09* −0.11
HR negative (ref=positive) 0.29 −0.31 0.21 0.27 −0.27 0.18

p<0.05 *, p<0.01 **, p<0.0001* 25-month HRQOL scores are adjusted for HRQOL at 5-months.