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Yellow Light Hyperpolarizes eNpHR3.0-Expressing Pancreatic β Cells
(A) Voltage clamp (whole cell) recording of an eNpHR3.0-expressing β cell showing induction of photocurrents with yellow light (λ = 572 nm).
(B–D) Representative current clamp (perforated patch) recordings showing reversible membrane hyperpolarization with yellow light (λ = 572 nm) in an eNpHR3.0-expressing (NpHR), but not wild-type (WT), β cell. In all cases, n = 6–11 cells.
Data are means ± SEM. ∗∗∗p < 0.001.
