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. 2016 Sep 22;7:1436. doi: 10.3389/fpsyg.2016.01436

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Copyright © 2016 Zou, Song, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of brain functional alteration between drug addiction and romantic love. (A) Alterations in functional activation in brain regions involved in love and addiction. Red, love-related functional activation; green, addiction-related functional activation; blue, overlap of functional activation for love and addiction. (B) Alterations in resting-state functional connectivity (rsFC) for love and addiction. Green, addiction-related functional connectivity increase; Red, love-related functional connectivity increase; blue, overlap functional connectivity increase for love and addiction; purple, addiction-related functional connectivity decrease. ACC, anterior cingulated cortex; vACC, ventral anterior cingulate; dACC, dorsal anterior cingulate cortex; PCC, posterior cingulate cortex; OFC, orbitofrontal cortex; IFG, inferior frontal gyrus; dlPFC, dorsolateral prefrontal cortex; PFC, prefrontal cortex; VTA, ventral tegmental area; NAC, nucleus accumbens; TPJ, temporo-parietal junction, HIP, hippocampus; HT, hypothalamus; TEP, temporal cortex.