Table 2.
Clinical and pathologic characteristics (after review) in the total population, the L1CAM-negative- and the L1CAM-positive tumours
| Clinico-pathologic characteristics | L1CAM-negative n = 85 |
L1CAM-positive n = 18 |
P-value |
|---|---|---|---|
| Mean age in years (range) | 59.7 (24–86) | 68.2 (47–81) | <0.01 |
| Postmenopausal | |||
| No | 21 (26.3 %) | 1 (6.7 %) | |
| Yes | 59 (73.7 %) | 14 (93.3 %) | 0.18 |
| Median BMI in kg/m2 (range) | 29.3 (18.7–53.6) | 27.1 (19.8–47.1) | 0.12 |
| Lymph nodes | |||
| Positive | 1 (5.6 %) | 0 (27.8 %) | |
| Negative | 17 (94.4 %) | 5 (100.0 %) | 1.00 |
| FIGO stage* | |||
| Low (I) | 66 (77.6 %) | 12 (66.7 %) | |
| High (II-IV) | 19 (22.4 %) | 6 (33.3 %) | 0.37 |
| Tumor grade | |||
| Low (1–2) | 75 (88.2 %) | 3 (16.7 %) | |
| High (3) | 10 (11.8 %) | 15 (83.3 %) | <0.01 |
| Myometrial Invasion | |||
| < 50 % | 54 (63.5 %) | 7 (38.9 %) | |
| > 50 % | 31 (36.5 %) | 11 (61.1 %) | 0.06 |
| Lymphovascular Space Invasion | |||
| Not present | 73 (85.9 %) | 7 (38.9 %) | |
| Present | 12 (14.1 %) | 11 (61.1 %) | <0.01 |
| Histology | |||
| Endometrioid | 85 (100 %) | 7 (38.9 %) | |
| Non- endometrioid | 0 (0.0 %) | 11 (61.1 %) | <0.01 |
| Radiotherapy | |||
| No | 49 (57.6 %) | 13 (81.3 %) | |
| Yes | 36 (42.4 %) | 3 (18.8 %) | 0.10 |
| Mean follow-up in months (range) | 60.4 (0.4–148.0) | 51.1 (0–147.0) | 0.40 |
*2009 International Federation of Gynecology and Obstetrics staging system