Table 1.
Summary of the clinical features present in first 6 months from diagnosis, and over the whole disease course in a cohort 46 children with Behçet’s disease in a single UK paediatric rheumatology tertiary centre
| Number (%) with feature in the first 6 months (N = 46) | Number (%) with feature in whole disease course (N = 46) | |
|---|---|---|
| Recurrent oral ulceration | 38 (82.6) | 45 (97.8) |
| Genital ulceration | 8 (17.4) | 34 (73.9) |
| Skin lesions | 5 (10.9) | 11 (23.9) |
| Pustular lesions | 1 (2.2) | 3 (6.5) |
| Skin ulceration | 1 (2.2) | 2 (4.3) |
| Erythema nodosum | 1 (2.2) | 2 (4.3) |
| Necrotizing folliculitis | 1 (2.2) | 2 (4.3) |
| Acneiform lesions | 1 (2.2) | 2 (4.3) |
| Pathergy* | 0 | 3/5 (60) |
| Ocular lesions | 1 (2.2) | 4 (8.7) |
| Anterior uveitis | 1 (2.2) | 2 (4.3) |
| Conjunctivitis | 0 | 2 (4.3) |
| Gastrointestinal manifestations | 12 (26.1) | 26 (56.5) |
| Abdominal pain | 4 (8.7) | 12 (26.1) |
| Gastrointestinal haemorrhage | 1 (2.2) | 2 (4.3) |
| Gastrointestinal ulceration | 2 (4.3) | 7 (15.2) |
| Anal/perianal ulceration | 2 (4.3) | 5 (10.9) |
| Recurrent diarrhoea | 3 (6.5) | 6 (13.0) |
| Fever | 13 (28.3) | 14 (30.4) |
| Arthritis | 4 (8.7) | 10 (21.7) |
| Neurological manifestations | 5 (10.9) | 13 (28.3) |
| Seizure | 0 | 1 (2.2) |
| Frequent headache | 5 (10.9) | 11 (23.9) |
| Vascular complication | 2 (4.3) | 3 (6.5) |
| Sagittal sinus thrombosis | 1 (2.2) | 2 (4.3) |
| Thrombophlebitis | 0 | 1 (2.2) |
| Serositis | ||
| Pericardial effusion | 1 (2.2) | 1 (2.2) |
*Pathergy test was only performed in five patients, and was positive in 3/5