Table 4.
Comparison of present UK study cohort to other published studies on childhood Behçet’s disease
| Study (reference; country) | No. of patients | Male:female ratio | Median age of onset (year) | Percentage of patients in the series with each clinical features | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OU (%) | GU (%) | Skin (%) | Ocular (%) | Pathergy (%) | Arthralgia/arthritis (%) | GI (%) | NS (%) | Vascular (%) | ||||
| Present study | 46 | 1:1.09 | 4.87 | 97.8 | 74 | 32.6 | 8.7 | 60a | 52 | 58.7 | 32.6 | 6.5 |
| Koné-Paut et al. (21; International) | 110 | 1:0.96 | 8.2 | 83 | 61 | 57 | 33.9 | 44.7 | N/A | 26 | 29.3 | 13 |
| P value | 0.8608 | 0.0082 | 0.1434 | 0.0081 | 0.0012 | 0.6569 | 0.0002 | 0.7038 | 0.3984 | |||
| Kitaichi et al. (20, Japan) | 135 | 1:0.53 | 11.7 | 94.8 | 53.5 | 67.4 | 29 | N/A | N/A | N/A | N/A | N/A |
| P value | 0.0537 | 0.6816 | 0.0157 | 0.0001 | 0.0048 | |||||||
| Kim et al. (19; Korea) | 40 | 1:1.5 | 10.6 | 100 | 82.5 | 72.5 | 27.5 | N/A | 27.5 | 5 | 2.5 | N/A |
| P value | 0.5183 | 1.000 | 0.4370 | 0.0003 | 0.0259 | 0.0001 | 0.0278 | 0.0002 | ||||
| Karincaoglu et al. (8; Turkey) | 83 | 1:1.18 | 12.3 | 100 | 81.9 | N/A | 34.9 | 37 | 39.8 | 4.8 | 7.2 | 16.8 |
| P value | 0.8554 | 0.3566 | 0.3664 | 0.0013 | 0.3703 | 0.1980 | 0.0001 | 0.0003 | 0.1110 | |||
| Lang et al. (22; Canada) | 37 | 1:0.947 | 8.7 | 100 | 75 | 84 | 30 | N/A | 54 | 40 | 32 | 16 |
| P value | 0.8267 | 1.0000 | 1.0000 | 0.0001 | 0.0204 | 1.0000 | 0.1244 | 1.0000 | 0.1783 | |||
P values were calculated by Fisher exact test. P values less than 0.05 (two-sided) were considered significant
OU oral ulceration, GU genital ulceration, GI gastrointestinal, NS nervous system, N/A data not available
aPathergy test was only performed in five patients, and was positive in 3/5