Figure 2.

(a) Low power microscopic view of the accessory spleen showing marked congestion and a nodular pattern (hematoxylin and eosin stained section, magnification ×20). (b) High power view shows extramedullary hematopoiesis including atypical megakaryocytes (hematoxylin and eosin stained section, magnification ×400). (c) Small cells with occasional cytoplasmic vacuoles resembling lobular carcinoma cells infiltrate the fatty tissue (hematoxylin and eosin stained section, magnification ×400). (d) Cytokeratin stain highlights numerous cells that represent metastatic carcinoma (magnification ×100). (e) Estrogen receptors and (f) GATA3 strongly stain the nuclei of the cancer cells confirming the mammary origin of the cancer ((e) and (f) magnification ×200).