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Correlation between IL-6 plasma levels and BM fibrosis, splenomegaly, number of circulating CD34 + cells, and hemoglobin values. Irrespective of mutational status, IL-6 plasma levels correlated with BM fibrosis (p = 0.0056; r = 0.49), splenomegaly (p = 0.018; r = 0.46), and the absolute number of circulating CD34+ cells (p = 0.029; r = 0.48) and negatively correlated with hemoglobin values (p = 0.047; r = −0.39); (a, b, c, and d, resp.). x-axis of (a) shows BM fibrosis scale.
