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. 2016 Jun 10;71(10):2868–2873. doi: 10.1093/jac/dkw214

Table 2.

In vitro susceptibilities of Candida and Aspergillus spp. to CD101 as determined by 24 h CLSI and EUCAST BMD methods using prominent (≥50%) MIC endpoint criteria

Species (no. tested) Test method CD101 MIC or MEC (mg/L)
Percentage EA
range mode
C. albicans (25) CLSI ≤0.008–1 0.015 92.0
EUCAST ≤0.008–1 ≤0.008
C. glabrata (25) CLSI 0.015–2 0.06 100.0
EUCAST ≤0.008–2 0.06
C. tropicalis (21) CLSI ≤0.008–1 0.015 100.0
EUCAST ≤0.008–0.5 0.03
C. krusei (20) CLSI 0.015–1 0.06 100.0
EUCAST 0.03–0.5 0.06
C. parapsilosis (15) CLSI 0.5–2 1 100.0
EUCAST 0.5–1 1
A. fumigatus (20) CLSI ≤0.008–0.06 ≤0.008 95.0
EUCAST ≤0.008–0.03 0.015
A. terreus (19) CLSI ≤0.008–0.03 ≤0.008 100.0
EUCAST ≤0.008–0.03 ≤0.008
A. flavus (12) CLSI ≤0.008–0.015 ≤0.008 100.0
EUCAST ≤0.008–0.03 ≤0.008
A. niger (16) CLSI ≤0.008–0.03 ≤0.008 100.0
EUCAST ≤0.008–0.03 ≤0.008