Table 1.
Sociodemographic, clinical profile, delirum subtype, Delirium Rating Scale-Revised-98 and mini mental status examination ratings for both the study groups
| Variables | Haloperidol n = 32 mean (SD) | Quetiapine n = 31 mean (SD) | χ2/t-test |
| Age (yr) | 44.40 ± 16.76 (range 18-76) | 48.51 ± 19.75 (range 18-85) | 0.89 (P = 0.37) |
| Age ≥ 60 yr | 7 (32%) | 12 (38.7%) | 2.11 (0.146) |
| Education (No. of years) | 9.81 ± 4.46 (range 0-15) | 9.38 ± 4.03 (range 0-17) | 0.396 (P = 0.693) |
| Male | 28 (87.5%) | 21 (67.74%) | 3.55 (P = 0.06) |
| Locality- Urban | 21 (65.6%) | 24 (77.4%) | 1.073 (P = 0.300) |
| Type of onset - hospital emergent | 23 (71.87%) | 25 (80.64%) | 0.668 (P = 0.414) |
| Duration of delirium prior to assessment (d) | 2.38 ± 1.81 | 2.83 ± 2.32 | 0.85 (P = 0.398) |
| Total IQCODE | 3.01 ± 0.053 | 3.13 ± 0.40 | 1.57 (0.12) |
| Delirium subtype as per amended DMSS | |||
| Hyperactive | 28 (87.5%) | 27 (87.09%) | |
| Hypoactive | 5.36 (P = 0.76) | ||
| Mixed | 3 (9.37%) | 2 (6.45%) | |
| 1 (3.12%) | 2 (6.45%) | ||
| Mean dose (mg/d) | 0.67 ± 0.35 (range 0.25-1.25) | 26.63 ± 15.61 (range 12.5-75) | |
| Mean number of etiologies | 7.06 ± 3.31 | 6.58 ± 3.92 | 0.52 (P = 0.60) |
| DRS-R-98 total score at baseline | 31.21 ± 2.40 | 31.83 ± 4.10 | 0.73 (P = 0.46) |
| DRS-R-98 scores (severity items only) | |||
| Day 0 | 24.81 ± 2.19 | 25.48 ± 3.60 | 0.89 (P = 0.37) |
| Day 1 | 20.46 ± 3.93 | 19.54 ± 6.40 | 0.68 (P = 0.49) |
| Day 2 | 15.43 ± 6.19 | 13.54 ± 7.67 | 1.07 (P = 0.28) |
| Day 3 | 11.46 ± 6.58 | 9.51 ± 7.29 | 1.11 (P = 0.26) |
| Day 4 | 8.65 ± 6.73 | 7.83 ± 7.42 | 0.45 (P = 0.64) |
| Day 5 | 6.46 ± 6.06 | 6.48 ± 6.84 | 473 (P = 0.749)1 |
| Day 6 | 5.43 ± 5.84 | 5.58 ± 5.84 | 466.5 (P = 0.679)1 |
| DRS-R-98 < 10 on day 0 | 0 | 0 | - |
| DRS-R-98 < 10 on day 1 | 0 | 3 (9.67%) | FE = 0.11 |
| DRS-R-98 < 10 on day 2 | 5 (15.62%) | 8 (25.80%) | 0.99 (P = 0.31) |
| DRS-R-98 < 10 on day 3 | 14 (43.75%) | 16 (51.61%) | 0.39 (P = 0.53) |
| DRS-R-98 < 10 on day 4 | 21 (65.62%) | 20 (64.51%) | 0.009 (P = 0.92) |
| DRS-R-98 < 10 on day 5 | 23 (71.85%) | 22 (70.96%) | 0.006 (P = 0.93) |
| DRS-R-98 < 10 on day 6 | 22 (68.75%) | 21 (67.74%) | 0.007 (P = 0.93) |
| MMSE scores | |||
| Day 0 | 7.50 ± 3.83 | 6.83 ± 4.45 | 0.63 (P = 0.53) |
| Day 1 | 11.31 ± 5.91 | 11.80 ± 6.02 | 0.328 (P = 0.74) |
| Day 2 | 15.50 ± 5.16 | 16.00 ± 6.37 | 0.343 (P = 0.73) |
| Day 3 | 18.28 ± 0.73 | 18.38 ± 6.26 | 0.070 (P = 0.94) |
| Day 4 | 20.34 ± 5.72 | 20.67 ± 6.41 | 0.218 (P = 0.828) |
| Day 5 | 21.93 ± 5.01 | 21.58 ± 5.74 | 0.263 (P = 0.794) |
| Day 6 | 23.00 ± 4.75 | 22.54 ± 5.34 | 0.354 (P = 0.724) |
1
Mann-Whitney U value. DRS-R98: Delirium Rating Scale-Revised-98; MMSE: Mini mental status examination; FE: Fisher Exact test.