Figure 2. RRs and 95% CIs for tumor incidence in genetically engineered and chemically induced animal models.
The pooled estimates were obtained using a random-effects model. The dots indicate the RRs comparing ICR to CCR. The size of the shaded square is proportional to the weight in each study. The horizontal lines represent the 95% CIs. The diamond data markers indicate the pooled RRs with corresponding 95% CIs. CCR: chronic calorie restriction; CI: confidence interval; ICR: intermittent calorie restriction; RR: relative risk (for tumor incidence).