Table 1. Characteristics of the five parasite proteins selected as potential CBPs.
Name in PlasmoDB | Gene Family | Acronym | Chromosome number | mRNA (bp) | Intron number | Signal peptide | TM number | Sequence (AA) | MW (Da) with signal peptide | MW (Da) without signal peptide |
---|---|---|---|---|---|---|---|---|---|---|
PF3D7_0113900 GEXP10 | hyp8 | CBP1 | 1 | 732 | 1 | Yes | 2 | 243 | 28234 | 25320 |
PF3D7_1301700 GEXP07 | hyp8 | CBP2 | 13 | 738 | 1 | Yes | 2 | 245 | 28255 | 25328 |
PF3D7_0501000 | 5 | 783 | 1 | No | 1 | 260 | 30716 | |||
PF3D7_1478100 | hyp13 | 14 | 744 | 1 | Yes | 2 | 247 | 28657 | 25553 | |
PF3D7_1102600 GEXP14 | 11 | 816 | 1 | No | 3 | 271 | 32328 |
Among the hits with significant scores identified by proteomics, five genes coding for proteins with a 20–35 kDa molecular mass and containing a Pexel motif were selected. Their characteristics are displayed according to the PlasmoDB (http://plasmodb.org/plasmo/).