Table 3. Correlation between imaging score and treatment response after NAC (n = 48, pCR = pathological complete response.

	pCR Mean ± SD (range)	non-pCR Mean ± SD (range)	p value	r	MHR Mean ± SD (range)	NMHR Mean ± SD (range)	p value	r
3D-CEUS score	0.5 ± 1.4 (0–4)	3.9 ± 1.7 (1–8)	0.0001	−0.573	2.1 ± 1.7 (0–4)	4.2 ± 1.9 (1–8)	0.0002	−0.541
DCE-MRI score	0.3 ± 0.7 (0–2)	3.9 ± 1.9 (0–8)	<0.0001	−0.615	1.5 ± 1.5 (0–4)	4.6 ± 1.6 (2–8)	<0.0001	−0.702
Δ3D-CEUS	8.1 ± 1.1 (6–9)	3.4 ± 1.5 (2–6)	<0.0001	0.649	6.5 ± 1.7 (4–9)	2.6 ± 0.7 (2–4)	<0.0001	0.863
ΔDCE-MRI	8.0 ± 1.1 (7–9)	3.5 ± 1.7 (1–7)	<0.0001	0.639	6.4 ± 1.6 (5–9)	2.7 ± 1.2 (1–5)	<0.0001	0.836

MHR = major histological response. NMHR = non-major histological response. DCE-MRI = dynamic contrast enhanced magnetic resonance imaging. 3D-CEUS = three dimensional contrast enhanced ultrasound. Δ3D-CEUS = score difference before and after treatment. ΔDCE-MRI = score difference before and after treatment).