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. 2016 Sep 22;6:33947. doi: 10.1038/srep33947

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Copyright © 2016, The Author(s)

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(a) A heat map illustrates selected mature miRNAs with levels significantly changed in OIR retinas at P17, as analyzed from array results. Red indicates up-regulated expression levels; green indicates down-regulated expression levels, as compared with mean levels from three normoxic control samples. (b,c) Significant fold-changes of miRNAs in OIR retinas versus normoxic controls expressed in log₂ scale. Eight miRNAs (miR-351, -762, -210, -145, -486, -339, -34c, and -155) were substantially up-regulated (b), and nine miRNAs (miR-129-5p, -150, -375, -203, -239-3p, -449a, -383, -1907 and -409) were substantially down-regulated in OIR retinas (c). Data were presented as mean ± standard error of the mean (SEM).