Figure 2. NOR-1 knockdown down-regulates cIAP2 expression in VSMC.

Human VSMC were transfected with a siRNA against NOR-1 (siNOR-1, ID s15541; black bars) or a random siRNA (siRandom; white bars). (a) The expression of NOR-1 and that of cIAP2 in these samples was analyzed by real-time PCR (n = 6). *P < 0.0001 vs. siRandom. (b) The down-regulation of cIAP2 by siNOR-1 was also confirmed by western blot. Levels of β-actin were used as a loading control.