Table 2.

The dependence between MACC1 expression and clinicopathological features in cancer patients

Cancer	The correlation of MACC1 protein/mRNA expression with demographic and clinicopathological features
	Patient age	Gender	Histopathology	TNM or other staging	Prognostic significance		Ref.
					Lower OS	Lower DFS
Colorectal carcinoma	no	no	no	no	–	–	[36]
	–	–	yes	yes	–	–	[9]
	–	–	–	–	yes	yes	[1, 37–40]
Gastric carcinoma	yes	no	no	yes	yes	–	[44]
	no	no	no	no	–	–	[45–47]
	–	–	–	–	yes	yes	[16]
Hepatocellular carcinoma	–	–	yes	yes	–	–	[18, 49]
	–	–	–	–	yes	yes	[49, 50, 52, 53]
Gallbladder carcinoma	no	no	yes	yes	yes	–	[22]
Pancreatic carcinoma	no	no	–	yes	–	–	[23]
Oesophageal carcinoma	no	no	no	yes	yes	–	[58, 59]
Naso-pharyngeal carcinoma	no	no	no	yes (only N)	–	–	[24]
Lung carcinoma	no	no	yes	yes	–	–	[60, 63]
	–	–	–	–	yes	yes	[60–62]
Breast carcinoma	–	–	–	yes	yes	yes	[64]
Ovarian carcinoma	–	–	–	yes	yes	–	[66]
Cervical carcinoma	–	–	–	yes	yes	–	[67]
Renal carcinoma	–	–	yes	yes	yes	yes	[68]
Glioma	no	no	yes	no	yes	–	[69]
Osteosarcoma	no	no	–	yes	yes	–	[71]