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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Cell Signal. 2016 Aug 10;28(11):1735–1741. doi: 10.1016/j.cellsig.2016.08.005

Figure 3. Pharmacological inhibition of HuR reduces hypertrophic cell growth and ANF expression.

Figure 3

(A) NRVMs were treated simultaneously with PE and two novel small molecule inhibitors of HuR described by Wu et al.[13]. Hypertrophic growth was assessed 24 hours later via WGA staining. (B) Cell surface area was quantitatively determined using NIH Image J. N=6 for each group (each N represents the average measurement of 10 cells per well). *P ≤ 0.05. (C) Total RNA was also isolated from a subset of cells and expression level of ANF was assessed by qRT-PCR. *P ≤ 0.05.