Figure 3.

Function and structure in RHO mutation patients with milder class B phenotypes. (A) P4, with a T17M mutation. Kinetic field is normal. Sensitivity profiles reveal a pericentral defect in the superior field–inferior retina, and colocalized OCT indicates a structural correlation. (B) P6, with a P23H mutation. Kinetic field has a full extent with V-4e but some limitation with I-4e. Only the dark-adapted sensitivity profile reveals a pericentral defect, and this is in the inferior field–superior retina. A structural correlate at this pericentral location is noted on OCT, although there is also a more generalized reduction in ONL and ROS thickness in this patient, except for the central few degrees.