Figure 2.
Meta‐analysis: effects of CSII and MDI on HbA1c in adult and paediatric patients with T1DM 7. A meta‐analysis of 12 randomised controlled trials involving a comparison of CSII and MDI in adult patients with T1DM demonstrated a statistically significant difference in HbA1c in favour of CSII of 0.29% (95% CI, 0.06% to 0.52%). In paediatric patients, meta‐analysis of eight trials also favoured CSII (0.22% [0.03% to 0.41%]). CI, confidence interval; CSII, continuous subcutaneous insulin infusion; MDI, multiple daily injections; NPH, neutral protamine Hagedorn; T1DM, type 1 diabetes mellitus