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. Author manuscript; available in PMC: 2017 Sep 16.
Published in final edited form as: Phys Rev Lett. 2016 Sep 13;117(12):128101. doi: 10.1103/PhysRevLett.117.128101

FIG. 1. A stochastic model of nascent RNA kinetics.

FIG. 1

(a) Model schematic. (b) Different experimental observables that can be described by the model: The number of RNA polymerases (RNAPs) on the gene (green), the amount of nascent RNA (red), and the signal from single-molecule fluorescence in situ hybridization (smFISH) probes (blue). (c) The contribution function corresponding to the three observables in panel b. In all cases, TS = 0.