Table 1.
Characteristics of TrialNet autoantibody-positive subjects (n = 1,287)
| Characteristics | Ab+ subjects without diabetes (n = 1,110) | Ab+ subjects with diabetes (n = 177) | P value |
|---|---|---|---|
| Age at initial visit (years) | 16 (9–37) | 10 (7–14) | <0.0001 |
| Age at last visit (years) | 19 (12–39) | 11 (8–17) | <0.0001 |
| Sex, female | 669 (60) | 88 (50) | 0.02 |
| Multiple (≥2) Ab+ at initial visit | 249 (22) | 136 (77) | <0.0001 |
| HLA DR3/4-DQ8 (yes) | 71 (15) | 33 (25) | 0.007 |
| BMI at initial visit (% underweight/normal/overweight/obese) | 1/57/22/20 | 2/62/18/18 | 0.35 |
Data are median (IQR) or n (%), unless specified otherwise. Boldface type indicates P < 0.05. Ab+, autoantibody positive.