Table 2.

Incidence of diabetes incidence and risk reduction and numbers needed to treat in D-CLIP intervention and control participants by population subgroup

	N	Incidence density (cases/100 person-years)		Reduction in incidence*		Number needed to treat
		Control	Intervention	%	95% CI	n	95% CI
Overall	550	14.2	9.8	32	7, 50	9.8	5.4, 53.9
Age, years†
≤35	96	14.5	10.4	34	−46, 70	4.0	2.1, 46.0
36–50	292	13.7	10.0	21	−21, 49	13.9	5.4, −25.0
≥51	162	15.1	9.0	47	6, 70	10.1	4.0, −20.6
Sex†
Male	344	14.5	9.6	37	7, 58	9.2	4.7, 245.6
Female	206	13.9	10.1	24	−27, 54	12.0	4.6, −19.0
BMI, kg/m2†
23 to <27.5	246	10.5	8.7	14	−43, 48	46.3	10.9, −20.5
≥27.5	273	19.1	10.5	49	23, 66	6.8	4.3, 16.6
Prediabetes type†
iIFG	166	7.2	6.5	12	−80, 57	15.5	7.8, 854.4
iIGT	162	10.7	7.4	31	−31, 64	11.0	5.4, −188.3
IFG+IGT	222	22.2	14.5	36	3, 57	12.3	5.4, −43.6
HbA1c, % (mmol/mol)†
<5.7 (<39)	117	7.7	6.1	13	−106, 64	19.3	7.9, −43.1
5.7–6.4 (39–46)	340	15.3	8.1	50	25, 67	8.2	5.2, 19.6
≥6.5 (≥48)	93	19.4	20.3	−18	−114, 35	256.4	5.9, −6.2
Family history†
No	200	12.8	7.3	46	5, 70	8.3	3.8, −55.5
Yes	349	15.1	11.3	23	−12, 47	10.8	5.1, −80.1

*Based on the hazard ratio.

†Tests for heterogeneity across strata were not statistically significant except for HbA_1c (P = 0.05).