Table 3. Odds ratio and 95% confidence interval for prognostic outcomes according to serum soluble corin level.
| Prognostic outcomes | Low corin | High corin | Unadjusted | Age, NIHSS-adjusted | Multivariate-adjusted* | |||
|---|---|---|---|---|---|---|---|---|
| Cases (%) | Cases (%) | OR (95%CI) | P-value | OR (95%CI) | P-value | OR (95%CI) | P-value | |
| major disability, death, vascular events | 60 (36.14) | 98 (27.53) | 0.67 (0.45–0.99) | 0.047 | 0.65 (0.41–1.03) | 0.068 | 0.64 (0.39–1.04) | 0.069 |
| death or major disability | 54 (32.53) | 84 (23.60) | 0.64 (0.43–0.96) | 0.032 | 0.60 (0.36–0.99) | 0.047 | 0.61 (0.36–1.02) | 0.058 |
| death or vascular events | 25 (15.06) | 38 (10.67) | 0.67 (0.39–1.16) | 0.154 | 0.70 (0.40–1.23) | 0.216 | 0.67 (0.38–1.21) | 0.185 |
| death | 13 (7.83) | 18 (5.06) | 0.63 (0.30–1.31) | 0.215 | 0.66 (0.30–1.46) | 0.307 | 0.62 (0.27–1.41) | 0.257 |
| vascular events | 17 (10.24) | 24 (6.74) | 0.63 (0.33–1.21) | 0.169 | 0.65 (0.34–1.25) | 0.198 | 0.62 (0.32–1.22) | 0.171 |
High corin was defined as the upper two tertiles of serum soluble corin. Low corin was defined as the lowest tertile of serum soluble corin.
*Adjusted for age, sex, baseline NIHSS score, hours from onset to hospitalization, smoking, drinking, hypertension, diabetes, coronary heart disease, family history of stroke, atrial fibrillation, and stroke subtype.