Figure 2.

VWR exercise improves insulin sensitivity index and glucose tolerance in obese mice by decreasing fasting plasma insulin. Fasting plasma glucose (A) and insulin levels (B) were recorded as mg/dL and pmol/L, respectively. The insulin sensitivity index (C) was calculated based by multiplying fasting plasma glucose (mmol/L) by fasting insulin (ng/mL) values. Glucose tolerance test is shown in panels D and E. Data are mean ± SEM. *P < 0.05, diet effect; †P < 0.05, VWR effect. AUC, area under the curve; SED, sedentary.