Table 1. Characteristics of included participants by disease stage.
| n (%) | Age (±SD) | M:F ratio | CAG | TFC | TMS | Disease burden | |
|---|---|---|---|---|---|---|---|
| Total sample | 37 | 47 (±12) | 14:23 | ||||
| Healthy controls | 14 (38) | 44 (±13) | 4:10 | N/A | 13 | N/A | N/A |
| Pre-manifest | 3 (8) | 40 (±10) | 1:2 | 42 | 13 | 1 | 252 |
| Early stage | 15 (41) | 50 (±12) | 6:9 | 44 | 11 | 27 | 407 |
| Moderate stage | 5 (14) | 58 (±2) | 3:2 | 43 | 5 | 50 | 421 |
| Intergroup differences | p = 0.077 | p = 0.716 | p = 0.261 | p = 1*10−8 | p = 0.005 | p = 0.007 |
M:F, male to female ratio; CAG, Cytosine-adenosine-guanine repeats; TFC, total functional score; TMS, total motor score; N/A, not applicable.