Table 2. Characteristics of the included studies for the disease-free survival (DFS) analysis.
First author | Year | Country | Cancer | Stage | Follow up(M) | Case(N) | Treatment | Technique | Location of staining | Cut off | Disease-free Survival | NOS | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | ||||||||||||
HR (95% CI) | HR (95% CI) | ||||||||||||
Hroyasu N | 2015 | Japan | AC | I- III | 38.1* | 101 | pulmonectomy | IHC | Cytoplasm | >median score | 1.72(1.00–2.99) | 8 | |
Guan XQ | 2014 | China | NSCLC | I-IV | 60 | 500 | pulmonectomy | IHC | Cytoplasm | score≥3 | 1.015(0.800–1.287) | 8 | |
Zhang H | 2013 | China | SCC | I- IIIa | 51.5* | 204 | pulmonectomy | IHC | Cytoplasm | score≥4 | 1.474(1.117–1.944) | 1.164(0.873–1.552) | 8 |
Yasuhiro C | 2011 | Japan | NSCLC | I- III | 53.7* | 183 | pulmonectomy | IHC | NR | ≥50% | 1.326(0.634–2.770) | 1.144(0.535–2.443) | 8 |
NSCLC: non-small cell lung cancer, SCC: squamous cell carcinoma, AC: adenocarcinoma, IHC: immunohistochemistry, NOS: Newcastle-Ottawwwa-Scale.
*: median follow-up time.