Table 5. Prevalence of Vertebral Deformities Among Women in Selected Community and Population-Based Studies1,2,3.
| Author Year | Study | Imaging Technique and Deformity Grading Method | Age Strata and Sample Size | Number of Fractures per Stratum | Prevalence Estimate (95% CI) per 100 persons per stratum | |
|---|---|---|---|---|---|---|
| Melton 1993 | Rochester Epidemiology Project, Minnesota | Radiographs Melton [1989] | 50–54 | 106 | 11 | 10.4 (NR) |
| 55–59 | 137 | 16 | 11.7 (NR) | |||
| 60–64 | 112 | 14 | 12.5 (NR) | |||
| 65–69 | 107 | 18 | 16.8 (NR) | |||
| Ross 1995 | Hawaii Osteoporosis Study (HOS) Adult Health Study (AHS), Hiroshima | Radiographs Ross [1993] | Hawaii | |||
| 50–54 | 1 | NR | 0 (NR) | |||
| 55–59 | 15 | NR | 0 (NR) | |||
| 60–64 | 102 | NR | 1.0 (NR) | |||
| 65–70 | 313 | NR | 6.1 (NR) | |||
| Japan | ||||||
| 50–54 | 56 | NR | 5.4 (NR) | |||
| 55–59 | 147 | NR | 4.1 (NR) | |||
| 60–64 | 224 | NR | 4.9 (NR) | |||
| 65–69 | 159 | NR | 8.2 (NR) | |||
| Tsai 1996 | Taiwan Population Sample | Radiographs Eastell [1992] | 50–54 | 88 | 3 | 4.5 (0.2, 8.8) |
| 55–59 | 83 | 4 | 4.8 (0.2, 9.4) | |||
| 60–64 | 104 | 7 | 6.7 (1.9, 11.5) | |||
| 65–70 | 618 | 86 | 13.9 (11.6, 16.3) | |||
| O’neill 1996 | European Vertebral Osteoporosis Study | Radiographs Eastell [1992] McCloskey [1993] | McCloskey Method | |||
| 50–54 | NR | NR | 5.0 (NR) | |||
| 55–59 | NR | NR | 7.6 (NR) | |||
| 60–64 | NR | NR | 9.9 (NR) | |||
| 65–69 | NR | NR | 13.4 (NR) | |||
| Eastell Method | ||||||
| 50–54 | NR | NR | 11.5 (NR) | |||
| 55–59 | NR | NR | 14.6 (NR) | |||
| 60–64 | NR | NR | 16.8 | |||
| 65–69 | NR | NR | 23.5 | |||
| Ling 2000 | Beijing Osteoporosis Project | Radiographs4Black [1991] Eastell [1991] | Black Method | |||
| 50–59 | 100 | NR | 3.9 (0.2, 7.7) | |||
| 60–69 | 100 | NR | 10.5 (4.6, 16.3) | |||
| Eastell Method | ||||||
| 50–59 | 100 | NR | 4.9 (0.7, 91) | |||
| 60–69 | 100 | NR | 16.2 (9.2, 23.2) | |||
| Kadowki2010 | Japanese Population-Based Osteoporosis Cohort Study (JPOS) | DEXA5 McCloskey-Kanis [1993] | 50–59 | 260 | 7 | 2.7 (NR) |
| 60–69 | 246 | 34 | 13.8 (NR) | |||
| 70–79 | 1206 | 36 | 17.5 (NR) | |||
| Waterloo2012 | The Trøsmo Study | DEXA6 Kim semi-quantitative [Kim 2004] | 38–60 | 412 | 14 | 3.4 (NR) |
| 60–69 | 721 | 80 | 11.1 (NR) | |||
| 70–87 | 548 | 105 | 192. (NR) | |||
| Sanfelix-Gimeno2013 | Population-Based Study in Valencia, Spain (FRAVO) | Radiographs Genant semi-quantitative [Genant 1993] | 50–54 | 118 | 5 | 4.2 (NR) |
| 55–59 | 153 | 11 | 8.7 (NR) | |||
| 60–64 | 169 | 20 | 15.9 (NR) | |||
| 65–70 | 166 | 24 | 19.1 (NR) | |||
1 Studies tabulated are those that reported prevalence by 5- or 10- year age stratum in middle-aged women
2Except for semi-quantitative criteria, all vertebral deformity methods used a criterion of ≥3 standard deviation decrements from a referent standard (referent standards vary among
studies)
3NR = data not reported
4Investigators report that they sampled “approximately 100” in each stratum
5Hologic 4500A QDR with bone morphometric software
6Lunar prodigy